Liver diseases, or hepatic diseases, can present with different degrees of severity.

While alcohol abuse or being overweight are key factors, these diseases can also

be caused by an imbalance of the gut microbiota.

The Biocodex Microbiota Foundation supports research into the role of the microbiota

in alcoholic hepatitis. Analysis.

Alcoholic hepatitis, cancer, fibrosis, steatosis:

in 2019, 844 million people worldwide suffered

from a form of liver disease

(6)

. While obesity

and alcohol are the most common risk factors,

an imbalance of the gut microbiota is also

thought to be involved. Patients suffering from

a hepatic disease often present with dysbiosis

and an altered gut barrier. The most severe liver

alterations are often associated with the most

extreme forms of dysbiosis.

There is no longer any doubt about the role of microbiota

in these pathologies Modifying its composition through

prebiotics probiotics or a fecal transplant is one promising

line of research for preventive and curative treatments

There is a correlation between liver diseases

and certain bacterial populations found in the

gut. Current research focuses on the role of the

microbiota, especially certain bacterial species,

in the onset and development of alcoholic

hepatitis. Identifying the bacteria that determine

the severity of this type of hepatitis could pave

the way for new therapeutic strategies geared

to reducing the population of these harmful

bacteria

IN A NUTSHELL WHAT RESEARCH HAS TAUGHT US

MICROBIOTA AND

DISEASE MANAGEMENT

FOUNDATION

AWARDS

6 national grants

1 international grant

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